Raymond D. Smith is a scientist in our Orange County office.
Prior to joining the firm, Dr. Smith held scientist positions at two biotechnology companies. At Digital Gene Technologies Inc., he used the PCR-based TOGA method to compare mRNA expression profiles in tissue samples to identify gene targets for drug discovery. At Senomyx Inc., he used patch clamp electrophysiology to characterize the action of synthetic agonists on ion channels believed to be involved in human taste perception.
Dr. Smith received his Ph.D. in molecular neuroscience and subsequently worked as a postdoctoral scientist at the University of California, San Diego in the biology department.
Dr. Smith joined the firm in 2004.
National Institutes of Health Predoctoral Training Grant
“Regulation and Expression of Biological Processes”, 1989-1992
American Heart Association Postdoctoral Fellowship
“Ca2+ transients: Induction of genes in embryonic neurons", 1998-2000
Smith R.D. and Goldin A.L., Phosphorylation of Brain Sodium Channels in the I-II Linker Modulates Channel Function in Xenopus oocytes, J. Neurosci., March 1996, 16(6), 1965-1974.
Cantrell, A.R., Smith, R.D., Goldin, A.L., Scheuer, T., and Catterall, W.A., Dopaminergic Modulation of Sodium Current in Hippocampal Neurons via cAMP-Dependent Phosphorylation of Specific Site(s) in the Sodium Channel alpha Subunit, J. Neurosci., October 1997,17(19):7330-7338.
Smith, R.D., and Goldin, A.L., Functional Analysis of the Rat I Sodium Channel in Xenopus Oocytes, J. Neurosci., February 1998, 18(3):811-820.
Watt, S.D., Gu X., Smith R.D., and Spitzer, N.C., Frequency-encoded regulation of xGAD 67 transcript levels in Xenopus laevis spinal neurons, Mol Cell Neurosci., 2000 Oct, 16(4): 376-387.